Pennsylvania based McNeil was founded in 1879; in 1933 the company was incorporated as McNeil Laboratories, specializing in direct marketing of prescription pharmaceuticals to doctors, pharmacists and hospitals. in 1955 the first aspirin-free pain reliever for children, Tylenol®, was introduced; it was available only by prescription. By the 1960s the line of over-the-counter (OTC) Tylenol® options grew, along with adult versions of the drug; today the brand is the number one branded OTC analgesic in the United States. The pain reliever product line includes extra-strength caplets for adults; children's pain reliever/fever reliever in liquid form; adult's pain reliever caplets; acetaminophen liquid pain reliever for infants; cold and flu tablets; multi-symptom daytime cold relief tablets; sinus congestion and pain relief caplets; infant cough syrup; regular strength pain reliever; daytime sinus congestion and pain reliever and more pain relief solutions.